Resumo

BARRAGAN TORRES, Viviana Andrea et al. Essential oils, obesity and type 2 diabetes. Rev. colomb. cienc. quim. farm. [online]. 2017, vol.46, n.3, pp.289-302. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v46n3.69459.

The increase of obesity in our society has become evident nowadays. Recent statistics from official entities place it within the most prevalent diseases in the world. Obesity is a chronic pro-inflammatory disease that causes an imbalance in endocrine activity of adipose tissue, changing the production pattern of certain adipocytokines related to insulin resistance, consequently there is an increase of glycemia characteristic in type 2 diabetes mellitus. The treatment for these disorders is aimed to lower blood sugar levels and reduce the weight of those who suffer it. The medicines used to treat both diseases usually have undesirable side effects, which have made pharmacologists be in constant search for new drugs. The aim of this publication is to review the state of the art on these two diseases, starting from the fact that both have in common mild systemic inflammation and immunological alterations that lead to resistance to insulin action, and additionally to describe the activity of some essential oils studied so far in rats and mice as possible therapeutic alternatives in controlling obesity and type 2 diabetes mellitus.

Palavras-chave : Obesity; type 2 diabetes mellitus; inflammation; adipocytokines; essentials oils.

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