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Revista Colombiana de Ciencias Químico - Farmacéuticas
versão impressa ISSN 0034-7418
Resumo
CARABALLO MARIMON, Roger; URIBE MERLANO, Sergio e ALVIZ AMADOR, Antistio. Cost-effectiveness analisys ofrocuronium and succinylcholine in programmed thyroidectomy. Rev. colomb. cienc. quim. farm. [online]. 2017, vol.46, n.3, pp.357-370. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v46n3.69467.
The goal of this work was to perform a cost-effectiveness analysis of succinylcho-line and rocuronium used in the intubation of patients undergoing programmed thyroidectomy was compared by means of a prospective descriptive study, which included intubation quality, latency and muscle relaxation times, pharmacological reversion Neuromuscular blockade, hemodynamic parameters, adverse reactions and direct and indirect costs in 30 patients undergoing the procedure. The economic analysis evidenced the existence of significant differences between the costs associated with the latency time of muscle relaxation. Regarding the costs related to muscle blockade, it was observed that the succinylcholine group performed a total cost of 10972 ± 341.7 Colombian pesos, while with rocuronium it was 63088 ± 1184 with P value < 0.0001. Succinylcholine showed higher cost/effectiveness when presenting the shortest latency time, the best intubation conditions, no clinically significant cost changes and low cost when compared to rocuronium.
Palavras-chave : succinylcholine; rocuronium; cost-effectiveness; thyroidectomy.