Abstract

TKACH, Volodymyr V. et al. Lidocaine CoO(OH)-assisted electrochemical determination. A theoretical possibility to be evaluated. Rev. colomb. cienc. quim. farm. [online]. 2018, vol.47, n.1, pp.71-85. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v47n1.70659.

The electrochemical behavior of lidocaine during its electrooxidation over trivalent cobalt oxyhydroxide in lightly alkaline medium, realized for electroanalytical purposes, was evaluated from the mechanistic mathematical point of view. From analysis a conclusion has been made of the electroanalytical function of CoO(OH) as an electrode modifier for lidocaine electrooxidation in vivo and in vitro. Also, the possibility of oscillatory and monotonic instabilities has been verified in the system.

Keywords : Medication security; chemically modified electrodes; lidocaine; cobalt (III) oxyhydroxide; stable steady-state.

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