Resumo

VALENZUELA HUAMAN, César Joe et al. Effect of dry chloroformic and dichloromethane extracts of Tropaeolum tuberosum (Ruiz & Pavón) mashua on seminal parameters and acute toxicity. Rev. colomb. cienc. quim. farm. [online]. 2019, vol.48, n.1, pp.94-111. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v48n1.80068.

With the goal of proving the effect of chloroformic and dichloromethane dry extracts from Tropaeolum tuberosum R& P mashua, on the seminal parameters and its acute toxicity in albino mice. It was used two experimental groups and a control group. The mice were sacrificed, after 7 days while they were receiving the two kinds of extracts, making after that a sperm count, using for that the Neubauer's method and camera. The extracts, applied intraperitoneally, affect the amount of sperm on mice, getting: The group that received the chloroform extract showed a 79.9% decrease in the number of spermatozoids and the group that received the dichloromethane extract showed a decrease of 77.1%, both with respect to the control group.

Palavras-chave : Extract; seminal parameters; spermatogenesis; intraperitoneal; acute toxicity.

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