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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
BARROS GOMES, Paulo Roberto et al. Study of the chemical composition, toxicity and molluscicidal activity of the essential oil Citrus sinensis (L.) Osbeck. Rev. colomb. cienc. quim. farm. [online]. 2020, vol.49, n.1, pp.28-43. Epub Nov 10, 2020. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v49n1.87004.
In this present study, we determined the chemical composition and we tested the toxicity and the molluscicidal activity of the essential oil extracted from the barks of Citrus sinensis (L.) Osbeck. For this, the essential oil was extracted quantitatively by hydrodistillation. Then, quantifications of its components were performed by gas chromatography coupled to mass spectrometry (CG-MS) and the toxicity and molluscicidal activity were tested, respectively, against Artemia salina and snails Biomphalaria glabrata. The results showed that the oil contains 81.50% of D-limonene (main constituent) and 0.06% of citronellal (minor component) and it has lethal activity (LC50) of 100.08 mg.L-1 and a toxicity, with LC50 of321.84 mg.L -1 at a 95% confidence level. Therefore, the oil is active against the snail Biomphalaria glabrata and non-toxic to other living bein.
Keywords : Biomphalaria glabrata; hydrodistillation; compounds voltiles; Citrus sinensis (L.) Osbeck; schistosomiasis; Artemia salina.