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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
BARROS GOMES, Paulo Roberto et al. Chemical composition and larvicidal activity of essential oil of the bark of Citrus sinensis (L.) Osbeck. Rev. colomb. cienc. quim. farm. [online]. 2021, vol.50, n.1, pp.48-60. Epub Oct 27, 2021. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v50n1.95448.
Aim:
We determined the chemical composition and larvicidal activity of the essential oil distilled from the Citrus sinensis (L.) Osbeck husks and the pattern of the major constituent.
Materials and methods:
For this, we distill the oil by hydrodistillation, identify the components by gas chromatography coupled with mass spectrometry (GC-MS), test the larvicidal activity against Aedes aegypti and calculate the lethal concentration at 50% (LC50) by the Reed-Muench method and the confidence interval by the Pizzi method for both oil and standard.
Results:
It showed that the oil consists mostly of limonene and showed larvicidal activity (LC50 of 199.01 (± 2.10) μg-mL-1) greater than the lemonade standard (126.03 (± 2.09) μg-mL-1).
Conclusion:
Therefore, we conclude that distilled oil has the potential to replace chemical larvicides.
Keywords : Aedes aegypti; larvae; volatile compounds; Citrus sinensis (L.) Osbeck; distilled oil.
