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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
BAEZ, Margarita et al. Antioxidant and anti-inflammatory activity in hydroalcoholic extracts of Kalanchoe daigremontiana Raym. -Hamet & H. Perrier. Rev. colomb. cienc. quim. farm. [online]. 2021, vol.50, n.1, pp.86-99. Epub Oct 27, 2021. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v50n1.95450.
Aim:
To evaluate the antioxidant and anti-inflammatory activity in hydroalcoholic extracts of the aerial parts of Kalanchoe daigremontiana Raym. -Hamet & H. Perrier.
Materials and methods:
Extracts were obtained using ethanol (EtOH) and methanol (MeOH) as solvents at different concentrations. Total phenols and flavonoids were quantified using the Folin-Ciocalteu method and the aluminum complexation reaction, respectively.
Methodology:
The antioxidant activity of the extracts was determined using the DPPH» (2,2-diphenyl-1-picrylhydracil) free radical discoloration technique, while lipoxygenase (LOX) inhibition assays were used to measure the anti-inflammatory activity.
Results:
The 70% ethanolic extract showed a greater antioxidant capacity against DPPH» and a greater inhibition of the lipoxygenase enzyme, which should be related to the overall phenols and flavonoids content, suggesting that K. daigremontiana exhibits antioxidant and anti-inflammatory properties.
Keywords : Kalanchoe daigremontiana; polyphenols; antioxidants; anti-inflammatories.
