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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
TKACH, Volodymyr V. et al. The mathematical description of the electroanalytical determination of salvarsan drug and its cyclooligomers, assisted by the composite of squaraine dye with cobalt oxyhydroxide. Rev. colomb. cienc. quim. farm. [online]. 2021, vol.50, n.1, pp.205-216. Epub Nov 05, 2021. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v50n1.95453.
Aim:
In this work, the theoretical evaluation of the electroanalytical detection of antisyphilitic drug salvarsan is given for the first time. Cobalt oxyhydroxide in a composite with the squaraine dye is used as electrode modifier.
Methodology:
By means of the stability analysis the efficiency of the salvarsan determination is confirmed. The linearity of the dependence between the electrochemical parameter and drug concentration is easily obtained and maintained.
Conclusion:
The oscillatory and monotonic instabilities are realized in this system, being caused by the electrochemical stages' influences to the double electric layer (DEL).
Keywords : Salvarsan; electrochemical sensor; cobalt oxyhydroxide; squaraine dye; electrochemical oscillations; stable steady-state.
