SciELO - Scientific Electronic Library Online

 
vol.50 número1Atividade antioxidante de quatro espécies de plantas no Nordeste argentinoNitratos e nitratos dietéticos como possíveis causas de câncer: uma revisão índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista Colombiana de Ciencias Químico - Farmacéuticas

versão impressa ISSN 0034-7418versão On-line ISSN 1909-6356

Resumo

FREITAS, Laura Christina et al. Physico-chemical characterization, phytochemistry and evaluation of the antimicrobial efficacy of an herbal medicine gargle. Rev. colomb. cienc. quim. farm. [online]. 2021, vol.50, n.1, pp.253-268.  Epub 05-Nov-2021. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v50n1.95459.

Aim:

Considering the importance of natural products of traditional use, the work proposed the evaluation of quality parameters and in vitro antimicrobial activity of the gargle produced at the Popular Education Center (Cenep), Nova Palmeira (PB), and used for the treatment of oropharynx and tonsil disorders.

Methodology:

Three gargle samples were analyzed, in order to evaluate the microbiological aspect, the count of viable microorganisms was performed, by pour plate method.

Materials and methods:

The evaluation of antimicrobial activity in vitro against S. pyogenes was performed using the agar diffusion method and the physicochemical parameters determined were pH, dry residue, density, as well as phytochemical characterization.

Results:

They had microbial counts within the limits established by the pharmacopoeia. The antimicrobial activity against S. pyogenes had inhibition halos ranging from 10.5 to 18.6 mm for diluted and pure samples, respectively. The physical-chemical parameters showed pH 4.39 ± 0.16; the dry residue of 14.43 ± 1.00; and the density of 1.013 ± 0.010. The phytochemical profile was characterized by the presence of tannins, alkaloids and flavonoids.

Conclusion:

Thus, the gargle was suitable for use, considering the microbiological, physical-chemical, phytochemical parameters presented, as well as the proof of antimicrobial efficacy suitable for the proposed therapeutic use.

Palavras-chave : Phytotherapy; quality control; pharyngotonsillitis.

        · resumo em Português | Espanhol     · texto em Português     · Português ( pdf )