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Revista Colombiana de Ciencias Químico - Farmacéuticas
Print version ISSN 0034-7418On-line version ISSN 1909-6356
Abstract
PRIMON, Evelise Camila; DA ROCHA, Susana Beatriz; BONILHA DEZENA, Renan Marcel and DA SILVA, Gustavo Henrique. Study to determine the regenerative activity of tincture of Hamamelis virginiana L. (Hamamelidaceae), Maytenus ilicifolia Mart. ex Reissek (Celastraceae) and Casearia sylvestris Sw. (Salicaceae) in an experimental model using Escherichia coli cultures. Rev. colomb. cienc. quim. farm. [online]. 2023, vol.52, n.2, pp.826-841. Epub May 01, 2023. ISSN 0034-7418. https://doi.org/10.15446/rcciquifa.v52n2.110744.
Introduction
The induction of bacterial growth, in the experimental design used, was proposed as a strategy for evaluating the regeneration of epithelial tissue through the production of extracellular matrix by the fibroblast, collaborating with the healing process, in addition to inducing the production of glycocalyx in epithelial cells, facilitating adhesion and migration to recover the injured region.
Aim
To determine the action of the tinctures of Hamamelis virginiana, Maytenus ilicifolia and Casearia sylvestris on the growth of Escherichia coli cultures, to simulate, in this type of model, the potential regenerative activity of connective and epithelial cells, especially the fibroblast, by means of the disk-diffusion and spectrophotometric.
Results
The tinctures of Hamamelis virginiana, Maytenus ilicifolia and Casearia sylvestris at high and medium concentrations (above 1.6%) inhibit the development of Escherichia coli in culture, but at low concentrations (from 0.4 to 1.6%) induce bacterial proliferation, especially in the case of Maytenus ilicifolia and Casearia sylvestris tinctures.
Keywords : Hamamelis virginiana; Maytenus ilicifolia; Casearia sylvestris; Escherichia coli; spectrophotometric.












