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Revista Colombiana de Ciencias Químico - Farmacéuticas

Print version ISSN 0034-7418On-line version ISSN 1909-6356

Abstract

MOLINA DE SALAZAR, Dora Inés et al. Factors related to adherence to treatment in patients with chronic noncommunicable diseases in three Colombian cities. Rev. colomb. cienc. quim. farm. [online]. 2023, vol.52, n.2, pp.868-887.  Epub May 01, 2023. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v52n2.110746.

Aim

To present the preliminary report of the implementation of a pharmacotherapeutic follow-up (PF) program designed to improve the adherence of patients with chronic non-communicable diseases (NCDs) using the Dáder methodology.

Methods

prospective cross-sectional study in subjects ≥ 18 years with NCDs in 3 cities from Colombia. Data on the use of medications were collected through a virtual survey. The Dáder methodology was used, and the drug-related problems (DRP) and negative outcomes associated with medication (NOM) were classified according to the Granada Third Consensus. Additionally, adherence was assessed using The Medication Adherence Questionnaire (SMAQ) and the STOPP-START criteria were evaluated among the elder adults. Data was analyzed by descriptive statistics and the association between adherence and gender or age by Pearson's chi-squared test was evaluated.

Results

One hundred twelve subjects were evaluated with a predominance of female gender (72.3%) and mean age of 60.2 ± 10.9. The most encountered diagnoses were hypertension (58.9%) and type 2 diabetes mellitus (36.6%). Median number of medications per patient was 5 whit the interquartile range (IQR) 3-7. Non-adherence was identified in 7.25% and the main reason was attributable to the patient by 90%. No association between adherence and gender or age group was identified. Fifty-one DRP and 51 NOM were found with proposals to solve them.

Conclusion

The evaluation of pharmacological adherence through PF programs shows utility in the management of patients with NCDs.

Keywords : Adherence to medication; pharmacotherapeutic follow-up; cardiometabolic diseases; arterial hypertension; diabetes mellitus type 2.

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