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Revista Colombiana de Ciencias Químico - Farmacéuticas

Print version ISSN 0034-7418On-line version ISSN 1909-6356

Abstract

PEREIRA RODRIGUES, Antônio Rony da Silva  and  CARVALHO DE ALENCAR, Cicero Damon. Chemical profile and pharmacological activities of Punica granatum (Punicaceae): a review. Rev. colomb. cienc. quim. farm. [online]. 2023, vol.52, n.2, pp.1074-1096.  Epub May 01, 2023. ISSN 0034-7418.  https://doi.org/10.15446/rcciquifa.v52n2.107461.

Introduction

Punica granatum is the object of study by multiple researchers because the species has chemical compounds in leaves, roots, barks, juice, and stem, being a source of tannins, saponins, polyphenols, flavonoids among many other substances.

Aim

To describe the phytochemical profile and pharmacological activities of Punica granatum.

Methodology

The study is a bibliographic review focusing on articles published in the last decade (2013-2012), using the Scopus, Embase, Web of Science and PubMed-Medline databases as primary sources of research and using the free Ryyan software for analysis of the relevant studies that integrate the final review.

Results

The included studies describe pomegranate as a species rich in chemical compounds such as flavonoids, organic acids, and polyphenols. While pharmacological activities include anthelmintic, antidiabetic, anti-inflammatory, antimicrobial, anticarcinogenic activity and actions against the prevention and treatment of Alzheimer's disease.

Conclusion

The diversity of compounds may represent a viable source to produce drugs and cosmetics with activities of biological functions relevant to human health.

Keywords : Pomegranate; pharmacology; phytochemistry.

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