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Revista Colombiana de Obstetricia y Ginecología

Print version ISSN 0034-7434
On-line version ISSN 2463-0225


ZULETA TOBON, John Jairo. Hormone replacement therapy and cardiovascular disease: benefits explained by research bias. Rev Colomb Obstet Ginecol [online]. 2003, vol.54, n.2, pp.113-120. ISSN 0034-7434.

Although until time very recently the benefit of the hormone replacement therapy was accepted to prevent the coronary heart disease in postmenopausal women, now there are recommendations against it, these are born from the first controlled clinical trial that is devoted to the topic. A possible explanation to the contradiction between the observational studies that supported the employment and the clinical trial that doesn't find the benefits, can be the inherent biases to the first ones. It is carried out a revision of some of the biases that have already been demonstrated.

Keywords : Hormone replacement therapy; coronary heart disease; bias.

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