Resumen

ARENT, Adriana et al. Effect of cigarette smoking on laboratorial outcome of in vitro fertilization. Rev Colomb Obstet Ginecol [online]. 2004, vol.55, n.4, pp.287-292. ISSN 0034-7434.

Objective: to evaluate the influence of female cigarette smoking on laboratory results of in-vitro fertilization (IVF). Design: cohort study. Patients and methods: a total of 119 infertile couples, who were submitted to the first cycle of IVF due to tubal factor, were divided in three groups: non-smokers women (n=81), passive smokers women (n=15) and active smokers women (n=23). The laboratorial results of IVF were analyzed among the sub-groups. Results: women who smoked had a lower fertilization rate (40.7 %) and a worse embryo quality (70.6%) than the non-smokers (59% and 81.3%) and the passive smokers (67.4% and 87.9%) (p<0.05). There were no significant differences on the number of oocytes retrieved and embryo cleavage rate between the different groups. Conclusions: the results of this study indicate that the success of IVF can be affected negatively in the smoker women, due to smaller fertilization rate and the worse embryonic quality.

Palabras clave : tobacco; smoking; nicotine; infertility; IVF.

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