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Revista Colombiana de Obstetricia y Ginecología
Print version ISSN 0034-7434On-line version ISSN 2463-0225
Abstract
MADERO, José Ignacio et al. Importance of the response to the ovulation induction and the age in the result of the assisted reproduction techniques. Rev Colomb Obstet Ginecol [online]. 2004, vol.55, n.4, pp.293-299. ISSN 0034-7434.
Objective: the aim of the present study is to do an analysis about the efficacy of assisted reproduction techniques in a group of women with diminished response to ovary stimulation (three or less follicles at the end of stimulation process) and its correlation with age. Materials: we perform an analysis of 966 cases of patients who undergo to in vitro fertilization or intracytoplasmatic spermatozoids injection, 100 of these cases had poor response. Results: 80% of women in the group with poor response were 35 years or older, with 46% older than 40 years old. The mean of embryo transfer was 1.59 for the study group and 3.47 for the control group with an implantation rate of 11.34% and 12.34% respectively. The pregnancy rate was less within the poor response women group than (16.39%) than the control group (29.62%). Conclusions: our results suggest that women with poor response to ovulation induction, it means three or less follicles have higher risk of adverse results when they go through assisted reproduction techniques probably because of the presence of low oocytes counts limits the possibility to select the best embryos to transfer and increase the chance of obtaining embryos with abnormal chromosomal constitution.
Keywords : ovulation induction; poor responder; ovarian reserve; in vitro fertilization; ICSI; FSH; age.