Abstract

MLAYES, Linda et al. Managing mild to moderate male factor with L-carnitine: Case series. Rev Colomb Obstet Ginecol [online]. 2006, vol.57, n.4, pp.301-304. ISSN 0034-7434.

Objective: determining the efficacy of 1 gr of Lcarnitine applied via intramuscular route in treating mild to moderate male factor. Materials and methods: 12 men diagnosed as having mild to moderate oligo-astenoteratozospermia participated in the study. One group used 1 gr IM L-carnitine every 4 days for at least 2 months prior to the assisted reproductive procedure (with their partners). The spermatic parameters obtained on the day of the procedure were taken as a control. Results: the group which used L-carnitine for an average of 2 months showed a significant improvement in sperm concentration and mobility at the time of the assisted procedure, pregnancy being achieved in 50% of assisted reproduction cases. Conclusion: using L-carnitine improves sperm concentration and mobility, thereby improving pregnancy rate.

Keywords : male factor; L-carnitine; infertility.

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