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Revista Colombiana de Obstetricia y Ginecología

Print version ISSN 0034-7434On-line version ISSN 2463-0225

Abstract

SOSA, Cristian; GOMEZ, Libardo; BERMUDEZ, Carlos  and  PEREZ-WULFF, Juan. Increased foetal nuchal translucency and reverse flow of the ductus venosus in congenital cardiopathy. Rev Colomb Obstet Ginecol [online]. 2008, vol.59, n.1, pp.57-61. ISSN 0034-7434.

Introduction: increased foetal nuchal translucency (NT) from 11 to 14 weeks’ gestation is a common phenotypicexpressionofchromosomeabnormality, including trisomy 21. Nevertheless, in the absence of aneuploidy, nuchal thickening is clinically relevant because it is associated with increased adverse perinatal result caused by a variety of foetal malformations, dysplasias, deformations, disruptions and genetic syndromes. The object of presenting this case was to show the importance of NT as a marker for different aneuploid pathologies when being above the 99th percentile. Discussion: once the presence of aneuploidy has been eliminated, the risk of an adverse perinatal result does not become statistically reduced until nuchal measurement of translucency reaches 3.5 millimeters (99th percentile). Risk increases exponentially as NT increases. Nevertheless, if the foetus survives, there is an increased risk of congenital cardiopathy occurring. Ultrasound at 20-22 weeks can reveal cardiac abnormality.

Keywords : nuchal translucency; congenital heart disease; ductus venosus.

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