Abstract

HERRERA-ARIAS, Omaira del Socorro  and  DIAZ-CARDONA, Jaime. Immunohistochemistry in breast pathology. Differentiating complex benign and malign breast lesions: a case report and literature review. Rev Colomb Obstet Ginecol [online]. 2011, vol.62, n.3, pp.267-271. ISSN 0034-7434.

Objective: reviewing the histological basis and differential diagnostic criteria for applying immunohistochemistry in breast pathology. Clinical case: the case of a patient suffering from complex sclerosing lesion (CSL) of the breast, microglandular adenosis (MGA) pattern is presented; she required immunohistochemistry as an auxiliary technique for differentiating an adenocarcinoma-related breast lesion in situ and thus defining its treatment. Materials and methods: a search was made of the pertinent information in Medline databases via PubMed, SciELO and in books on the specialty; 25 titles were reported, 12 of them corresponding to the immediate topic: 4 were case reports with a literature review and one was a letter to the editor. 7 articles dealt with the topic in a more general way. Conclusion: immunohistochemistry led to the differential diagnosis of complex breast lesions such as sclerosing adenosis, and in situ or microinvase breast cancer.

Keywords : imunohistochemistry of the breast; sclerosing adenosis; breast lesions.

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