Abstract

MACHADO-ALBA, Jorge Enrique; MORALES-PLAZA, Cristhian David  and  OSSA-AGUIRRE, Diego Fernando. Compliance with pre-operative antibiotic therapy in obstetric and gynecological interventions at the San Jorge University Hospital in Pereira, Colombia, 2010: A cross-sectional study. Rev Colomb Obstet Ginecol [online]. 2013, vol.64, n.1, pp.38-45. ISSN 0034-7434.

Objective: To determine the degree of compliance with the antibiotic prophylactic guidelines in patients undergoing obstetric and gynecological surgery at the Hospital Universitario San Jorge de Pereira, Colombia. To conduct an exploratory analysis of the factors associated with non-compliance. Materials and methods: Cross-sectional descriptive study that enrolled all women undergoing surgery in the obstetrics and gynecology service of a tertiarycare hospital providing care to patients under the health regime subsidized by public funds, located in the Department of Risaralda, Colombia, between January 1st and December 31st, 2010. Patients whose clinical records did not reflect the time of administration of the antibiotic were excluded. A consecutive sampling was used. The assessment included social and demographic variables, the type of intervention, the type of wound, surgical risk, timeliness of antibiotic administration and the type of antimicrobials prescribed. Percent compliance is presented together with an exploratory analysis of factors associated with non-compliance, done using the SPSS 20.0 statistical package. Results: A total of 911 patients with a mean age of 28.6±10.2 years were intervened. Of them, 76.8% underwent Cesarean section and 18.7% abdominal hysterectomy. The antibiotics most commonly used were cefazolin (89.5%) and ampicillin (8.2%). Of the procedures, 42.0% complied with the guidelines. A statistically significant association was found with non-compliance with the guidelines, age under 18, and not use of cefazolin. Conclusion: Percent compliance was under 50%. This means that strategies must be put in place in order to improve the level of compliance with clinical practice guideline in this hospital.

Keywords : Clinical practice guidelines; medication adherence; anti-bacterial agents; surgical wound infection; Colombia.

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