SciELO - Scientific Electronic Library Online

vol.66 issue2Newton's and Laplace's determinism in the positive law of colombian legislation vs. Heinsenberg's uncertainty in medical practiceRetroperitoneal haematoma following vaginal hysterectomy with anterior and posterior vaginal wall repair in Bogotá, Colombia: Case report and review of the literature author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand



Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista Colombiana de Obstetricia y Ginecología

Print version ISSN 0034-7434


VASQUEZ-ARENAS, Mónica Isabel; ECHEVERRI-ALVAREZ, Lina; RENDON-PEREIRA, Gabriel  and  PAREJA-FRANCO, Rene. Neo-adjuvant chemotherapy as treatment for fertility preservation in patients with stage IB cervical cancer: Case presentation and review of the literature. Rev Colomb Obstet Ginecol [online]. 2015, vol.66, n.2, pp.124-130. ISSN 0034-7434.

Objective: To present the case of a patient with stage IB1 cervical cancer larger than 2 centimetres who received neo-adjuvant chemotherapy followed by laparoscopic radical cervicectomy and pelvic lymphadenectomy for fertility preservation; and to review the literature for case reports emphasizing obstetric and oncologic outcomes. Materials and methods: Case presentation and search of the literature in Medline through PubMed of articles published in English, French and Spanish between January 2000 and August 2014 on the topic of neo-adjuvant chemotherapy and fertility preservation surgery in patients with stage IB cervical cancer. Results: Overall, 12 relevant articles were selected totalling 55 patients. Over follow-up period ranging between 14 and 69 months there were 4 relapses and only one death attributable to the disease. Obstetric outcomes included 30 pregnancies, 24 births, 3 miscarriages, 1 ectopic pregnancy, and 2 on going pregnancies. Conclusion: Neo-adjuvant chemotherapy followed by conservative, fertility preservation surgery may be an option for the management of selected patients with stage IB cervical cancer involving large tumours sizes, who wish to preserve their fertility.

Keywords : Fertility preservation; uterine cervix neoplasms; chemotherapy; neo-adjuvant therapy; laparoscopy.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )