Abstract

MIRANDA, Ana Lucía; LOPEZ JARAMILLO, Carlos; GARCIA VALENCIA, Jenny  and  OSPINA DUQUE, Jorge. THE USE OF ENDOPHENOTYPES IN THE STUDY OF THE GENETIC COMPONENT IN SQUIZOPHRENIA. rev.colomb.psiquiatr. [online]. 2003, vol.32, n.3, pp.237-248. ISSN 0034-7450.

A review of the concept endophenotype from its historical origins to its actual conception is made. Besides, an approximation to the methodology used for detecting and validating an endophenotype and its advantages for studying the genetic component of psychiatric diseases, specifically schizophrenia, is performed.

Keywords : Endophenotype; genetics; schizophrenia.

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