Abstract

VALDERRAMA ESCUDERO, Felipe  and  MONTOYA GONZALEZ, Laura Elisa. Anticonvulsant Hypersensitivity Syndrome: A Case Report. rev.colomb.psiquiatr. [online]. 2014, vol.43, n.4, pp.225-228. ISSN 0034-7450.

DRESS syndrome (skin reaction with eosinophilia and systemic symptoms) is an idiosyncratic drug reaction characterized by rash, fever, lymphadenopathy, and internal organ dysfunction. This case report is on a patient with bipolar affective disorder who presented with a systemic inflammatory response associated with the use of valproic acid, and an important activation of symptoms when used with other drugs with a different pharmacological action mechanism. The diagnosis of DRESS syndrome is primarily by exclusion, and its detection may be difficult, which could potentially become fatal for the patient.

Keywords : Hepatic dysfunction; Valproic acid; Bipolar disorder.

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