SciELO - Scientific Electronic Library Online

 
vol.43 suppl.1Treatment of Adult Schizophrenic Patients With Depot AntipsychoticsPrevention and Treatment of Common Acute Adverse Effects With Antipsychotic Use in Adults With Schizophrenia Diagnosis índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista Colombiana de Psiquiatría

versão impressa ISSN 0034-7450

Resumo

GOMEZ-RESTREPO, Carlos et al. Pharmacological Treatment for Adult Diagnosed With Schizophrenia With Agitation or Violent Behavior. rev.colomb.psiquiatr. [online]. 2014, vol.43, suppl.1, pp.59-65. ISSN 0034-7450.  http://dx.doi.org/10.1016/j.rcp.2015.05.006.

Objectives: To determine the most effective pharmacological intervention and to bring recommendations for decision-making in the management of adults with schizophrenia with violent behavior or agitation. Methods: A clinical practice guideline was elaborated under the parameters of the Methodological Guide of the Ministerio de Salud y Protección Social to identify, synthesize and evaluate the evidence and make recommendations about the treatment and follow-up of adult patients with schizophrenia. The evidence of NICE guide 82 was adopted and updated. The evidence was presented to the Guideline Developing Group and recommendations, employing the GRADE system, were produced. Results: It is recommended the use of parenteral drugs in all agitated patient who does not respond to the measures of persuasion. The drugs with better evidence on effectiveness (control of violent behavior) are haloperidol and benzodiazepines, administered jointly or individually. Olanzapine is also an option considering that should only be used in institutions where a psychiatrist is available 24 hours. Ziprasidone can be considered as a second-line drug. The information about the side effects associated with these drugs is insufficient and has low quality. Conclusion: Violent behavior in adults with schizophrenia represents a risk for themselves and for those around them, so the opportune implementation of interventions aimed to calm the patient, in order to prevent potential negative outcomes is necessary. It is recommended to initiate these interventions with measures of verbal persuasion, and if these measures are not effective, appropriate use of parenteral drugs: haloperidol and benzodiazepines as first-line and olanzapine and ziprasidone as second choices.

Palavras-chave : Clinical Practice Guidelines; Schizophrenia; Violent behavior; Agitation; Self-harm; Hetero-aggression.

        · resumo em Espanhol     · texto em Espanhol     · Espanhol ( pdf )