Abstract

MARTINEZ, Miguel Restrepo; BAUTISTA, G. Paola; ESPINOLA-NADURILLE, Mariana  and  BAYLISS, Leo. Red flags for suspecting anti-NMDAr encephalitis in a first psychotic episode: report of two cases. rev.colomb.psiquiatr. [online]. 2019, vol.48, n.2, pp.127-130. ISSN 0034-7450.  https://doi.org/10.1016/j.rcp.2017.10.002.

Anti-N-methyl-D-Aspartate receptor (NMDAr) encephalitis is a recently described clinical entity with an increasing number of reported cases. Psychiatric symptoms in the early stages of the disease constitute a diagnostic challenge for the treating physician. We present two clinical cases: clinical case 1, a 26-year-old man, and clinical case 2, an 18-year-old man; both presented with a first episode of psychosis and were hospitalized as psychiatric disorders. Subsequently, both cases were diagnosed as anti-NMDAr encephalitis. The high prevalence of psychiatric symptoms in anti-NMDAr encephalitis forces psychiatrists and neurologists to have a high degree of suspicion in the presence of atypical symptoms in patients evaluated for the first episode of psychosis.

Keywords : Anti N-Metil-Aspartate receptor; encephalitis; Encephalitis; Psychosis. Catatonia. Differential diagnosis. Mental disorders..

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