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Revista Colombiana de Psiquiatría

Print version ISSN 0034-7450


BAENA-OQUENDO, Stephen; GARCIA VALENCIA, Jenny; VARGAS, Cristian  and  LOPEZ-JARAMILLO, Carlos. Neuropsychological Aspects of Bipolar Disorder. rev.colomb.psiquiatr. [online]. 2022, vol.51, n.3, pp.218-226.  Epub Nov 24, 2022. ISSN 0034-7450.

Bipolar disorder (BD) is a chronic condition with serious consequences on the health and functionality of patients who suffer from it, with a high heritability and segregation, and a prevalence of between 1% and 2%. Neuropsychological deficits have been implicated as a very important issue related to BD prognosis, so a review was conducted of these deficits, the related factors and their functional consequences. It has been determined that the presence of neuropsychological deficits can vary in patients with BD according to their mood state, with a great influence of depressive symptoms on the cognitive variability of patients with respect to the general population and differences with respect to patients in the manic phase. In euthymic patients, the most affected cognitive domains are those of memory, attention, and executive function, associated with a more severe disease, sociodemographic vulnerability factors, and stable over time. A relationship has been found between poor cognitive performance, especially executive dysfunction, and objective functional deficit. Furthermore, cognitive differences have been outlined between BD and other serious mental illnesses that are described in the review.

Keywords : Bipolar disorder; Mania; Depression; Euthymic; Neuropsychological; Cognition; Functionality.

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