Resumo

RODRIGUEZ VELASQUEZ, Javier. Fractal behavior of T specify repertory against Poa p9 alergeno. rev.fac.med. [online]. 2005, vol.53, n.2, pp.72-78. ISSN 0120-0011.

Background: based on a linguistic analogy applied to the immune specific B and T repertoires the immune system it has been characterized by the degree of fractal complexity like the one observed in the natural languages. Material and methods: this study is the application of a mathematical law to the immune repertoire. The Zipf-Mandelbrot law, observed in the natural languages, was applied to the study of the specific T repertoire against the allergen Poa p9. Results: the scale behavior of the law was observed in the specific repertoire from an allergic patient, with a without alfa interferon, like in Th cells clones. Conclusion: complexity degree of T repertoire against Poa p9 allergen can be identified by fractal dimension, as a appropriate mathematical parameter to characterize the physiology of the immune system, this fractal behavior has general implications for the immunology.

Palavras-chave : Immune system; interferon type I; clone cells; allergens; T-Lymphocytes; Poa, Zipf-Mandelbrot law; fractal; fractal dimension.

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