Abstract

VARGAS-HERNANDEZ, Jhonny Eddison. Human Nutrigenomics: Effects of Food or Food Components on RNA Expression. rev.fac.med. [online]. 2016, vol.64, n.2, pp.339-349. ISSN 0120-0011.  https://doi.org/10.15446/revfacmed.v64n2.51080.

The Human Genome Project was the starting point of great progress in genetics science. Nowadays is clearly known that the deoxyribonucleic acid (DNA) is a complex molecule that shows dynamic interactions both within itself and with other cellular environment components. Likewise, it is known that the ribonucleic acid (RNA) is a fundamental molecule to understand an organism features and how it responds to environmental stimuli. Moreover, the epigenetics mechanisms combine all molecular events that establish the specific traits -anatomical, physiological, metabolic, etc.- of a defined biological entity. These aspects allow studying the interactions between genome and diet, which is highly relevant, since the intake of food -or its components- is one of the most important environmental factors to which an individual is exposed throughout their life, as this factor is able to define health condition positively or negatively. This article aims to provide an overview of the basic aspects that make up the "nutrigenomics" concept and to provide a state of the art of the current researches conducted in humans in vivo.

Keywords : Food; Nutrition; Gene Expression; RNA; Proteins.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )