Introduction:

In general, ulcers are more frequently observed in the duodenum than in the stomach. However, in areas with a high incidence of gastric cancer, peptic ulcers seem to have a different anatomical distribution, predominantly gastric localization.

Objective:

To perform a narrative literature review about the anatomical distribution of peptic ulcers in areas with high and low incidence of gastric cancer.

Materials and methods:

A structured literature search was performed in the ProQuest, EBSCO, ScienceDirect, PubMed, LILACS, Embase, Trip, SciELO and Cochrane Library databases using the terms "Peptic ulcer" AND "Stomach Neoplasm". The search was done in English with its equivalents in Spanish and was limited to observational studies, cohorts and cases and controls.

Results:

About 50 articles with relevant information for this review were retrieved.

Conclusion:

The available literature suggests that peptic ulcers predominate in areas where gastric cancer has a high incidence, while duodenal localization predominates in areas where the incidence of neoplasms is low.

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