SciELO - Scientific Electronic Library Online

 
vol.68 issue3Neurotoxical activity of Micrurus snake venom and methods for its analysis. A literature reviewEndocarditis caused by Leuconostoc lactis in an infant. Case report author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista de la Facultad de Medicina

Print version ISSN 0120-0011

Abstract

FERNANDEZ-CHAGUENDO, Claudia Marcela; GIRON-MERA, Ingrid Johana; MUNOZ-MORA, Darío Fernando  and  GONZALEZ-CUELLAR, Fabiola Eugenia. Candida auris osteomielitis: Case report. rev.fac.med. [online]. 2020, vol.68, n.3, pp.463-466.  Epub Nov 25, 2020. ISSN 0120-0011.  https://doi.org/10.15446/revfacmed.v68n3.75599.

Introduction:

Candida auris is an opportunistic yeast associated with multiple infections, which was first reported in 2009 in Tokyo, Japan. Provided that it has great antifungal resistance to azoles and amphotericin B, its treatment options are limited, and therefore an empiric therapy using echinocandins such as micafungin should be considered.

Case presentation:

A rare case of a 48-year-old male patient with osteomyelitis caused by C. auris was reported in the city of Popayán, Colombia. The patient had a history of femoral head fracture, paraplegia due to firearm-related injury and neurogenic bladder, and reported having experienced abundant purulent foul-smelling secretions through trochanteric right ulcer for 15 days. MRI images revealed myositis and bone intensity alterations, which allowed diagnosing him with osteomyelitis.

Due to repeated isolations of C. haemulonii in several bone samples, antifungal management was initiated. However, since no improvement in the patient's condition was observed, a culture was sent to the Colombian National Institute of Health to identify the pathogen considering the repeated isolations of C. haemulonii and its apparent resistance to antifungals. C. auris was finally confirmed as the pathogen.

Conclusion:

Osteomyelitis by C. auris is a rare entity, which must be considered when treating patients with predisposing risk factors such as long hospital stays, bearing in mind that this is an inpatient-associated opportunistic infection.

Keywords : Osteomyelitis; Candida auris; Drug Resistance, Fungal (MeSH).

        · abstract in Spanish     · text in English     · English ( pdf )