SciELO - Scientific Electronic Library Online

vol.69 issue2Could Entrustable Professional Activities mediate community-based teaching in care integration services? author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


Revista de la Facultad de Medicina

Print version ISSN 0120-0011


URIBE-VALENCIA, Mauricio Andrés; JURADO-DELGADO, Janeth; VELASQUEZ-TAFUR, Lina Marcela  and  CARDENAS-CARDONA, Luis Fernando. Gorlin-Goltz syndrome in an older black adult. Case Report. [online]. 2021, vol.69, n.2, e500.  Epub July 14, 2021. ISSN 0120-0011.


Gorlin-Goltz syndrome (GGS), or basal cell nevus syndrome (BCNS), is a rare genetic disease that induces the development of odontogenic keratocysts, skeletal malformations and neoplasms, especially multiple and recurrent basal cell carcinomas (BCC). This condition is rare in black people, being reported in this population in only 5% of the cases.

Case presentation:

A 68-year-old black man reported the constant appearance for approximately 4 years of multiple papules and non-pruritic and non-desquamating skin plaques, with hyperpigmented margins, of different sizes that grew gradually in scalp, left lower eyelid, arms, forearms, back, and lower limbs. Histopathological study showed multiple BCC, and imaging studies identified calcifications in the tentorium cerebelli and cerebral falx, as well as images suggestive of odontogenic cysts. Based on his clinical history, histopathologic and imaging findings, and physical examination, he was diagnosed with GGS.


This is the first case of GGS in an older black adult reported in Colombia. This case highlights the relevance of reviewing the medical records and performing a thorough physical examination when approaching the patient, as well as doing a comprehensive geriatric assessment, since they are key to diagnose this rare disease and initiate a timely multidisciplinary treatment. This will allow obtaining better outcomes in these patients.

Keywords : Basal Cell Carcinoma; Gorlin-Goltz Syndrome; Basal cell Nevus Syndrome; Elderly (MeSH).

        · abstract in Spanish     · text in English     · English ( pdf )