SciELO - Scientific Electronic Library Online

 
vol.19 issue1Blood chemistry in bullfighting cattle maintained under grazing conditions in Andes Mountains from Colombia. author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Revista Colombiana de Ciencias Pecuarias

Print version ISSN 0120-0690On-line version ISSN 2256-2958

Abstract

GONZALEZ S, Jenny P et al. Polymorphism in 1908STR1934 locus of the 3’ UTR of the Nramp1 bovine gene in eight cattle breeds. Rev Colom Cienc Pecua [online]. 2006, vol.19, n.1, pp.11-17. ISSN 0120-0690.

The Nrampl gene has been associated with natural resistance to intracellular microorganisms in several species including bovine. Recent evidence suggests an association between polymorphism in the 3’ untranslated region (3’ UTR) of this gene with resistance/susceptibility (R/S) to Brucella abortus as determined in vivo and in vitro. In this study we tested for the variability of the short tandem repeat (STR) within the 3’ UTR of Nrampl in six breeds of Colombian creole cattle (CCC) and compared the genotypes with those of Holstein and Brahman, which were recently introduced into this country. In CCC as well as in Holstein we found the allele 175 fixed in all populations. In Brahman, 175 allele was also present with a frequency of 0.467 but additionally, in this breed there appeared five other alleles and among them two previously unreported: 183 y 185; also was found the allele 189 in the Colombian creole Harton del Valle cattle, which is not previously reported. Together these results suggest that the 175 allele in the 3’ UTR Nramp1 may be an ancestral allele in cattle and if this is true the association previously reported with the R/S trait requires further evaluation.

Keywords : colombian creole cattle; microsatellite; Nrampl; 3’ UTR.

        · abstract in Spanish     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License