SciELO - Scientific Electronic Library Online

 
vol.32 número3Uso da análise multivariada fatorial para caracterizar o perfil de ácidos graxos não ramificados em fluido ruminal de bovinos índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados

Journal

Artigo

Indicadores

Links relacionados

  • Em processo de indexaçãoCitado por Google
  • Não possue artigos similaresSimilares em SciELO
  • Em processo de indexaçãoSimilares em Google

Compartilhar


Revista Colombiana de Ciencias Pecuarias

versão impressa ISSN 0120-0690versão On-line ISSN 2256-2958

Resumo

GALVIS, Rubén D; MADRID, Liset V  e  RAMIREZ-VASQUEZ, Nicolás. L-carnitine supplementation descreases hepatic triglyceride accumulation in Holstein cows during the transition period. Rev Colom Cienc Pecua [online]. 2019, vol.32, n.3, pp.166-174. ISSN 0120-0690.  https://doi.org/10.17533/udea.rccp.v32n3a01.

Background:

The increased use of body reserves observed during peripartum leads to higher needs of L-carnitine by cows, which is restrictive under the production conditions of Colombian high tropics.

Objective:

To evaluate the lipotropic potential of L-carnitine in Holstein dairy cows during the transition period to lactation. Methods: Twenty-one Holstein cows were fed 0, 100, or 200 g/d L-carnitine fumarate from d 260 of gestation to d 20 postpartum. Hepatic triacylglycerides concentration, total carnitine, free carnitine, acylcarnitine, and serum levels of non-esterified fatty acids (NEFA), β-hydroxybutyrate (β-HB) and urea were determined by spectrophotometry. Repeated measures analysis was used to determine the effects of dose, measurement period, and their interactions.

Results:

Hepatic triglycerides and the different forms of carnitine showed no difference between sampling periods (p>0.05). Hepatic triglycerides concentration was low and decreased in response to 200 g/d L-carnitine fumarate supplementation (p<0.05). This decrease in hepatic triglycerides could be due to increased fatty acid oxidation. L-carnitine supplementation significantly increased (p<0.05) blood urea concentration, possibly through stimulation of the urea cycle, as previously described in other species.

Conclusion:

Supplementation with L-carnitine decreased the hepatic concentration of triglycerides, possibly due to increased liver oxidation of fatty acids.

Palavras-chave : dairy cows; lipid metabolism; L-carnitine; lipidosis; lipotropic factors; metabolic disorders; peripartum.

        · resumo em Português | Espanhol     · texto em Inglês     · Inglês ( pdf )