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Acta Medica Colombiana

Print version ISSN 0120-2448

Abstract

CARMONA-FONSECA, Jaime. Relationship between cholinesterase levels and blood groups ABO and Rh. Acta Med Colomb [online]. 2006, vol.31, n.3, pp.104-112. ISSN 0120-2448.

Background: it is postulated that Rh negative pregnant women have significantly less plasma cholinesterase activity than the Rh positive, although others have not found this relationship. In addition, such association is not seen in non-pregnant women or in men. Objective: to find the relationship among ABO-Rh blood groups and the levels of erythrocytes and plasma cholinesterase, in the general population according to gender as well as in pregnant women. Methodology: descriptive, cross-sectional and prospective design. Samples from adult working population (18-59 years) were taken, they had not been previously exposed to inhibiting cholinesterase pesticides (ICP) and worked in companies affiliated to the Social Security, located in the Valle de Aburrá and the Near East of Antioquia, Colombia. Erythrocyte and plasma cholinesterase were measured by five different methods and the commercial serums were used to identify the phenotypes ABO and Rh. Results: the smallest values of the erythrocytes enzyme always corresponded to group B ­ negative Rh and the greatest values to group AB - positive Rh. This regularity was not observed in the plasma enzyme, however, the erythrocytes, plasma and total blood enzymes did not show significant difference according to neither group ABO or Rh factor within any layer region-gender. In this study, all the pregnant women were positive Rh and it was not possible to be evaluated the relation between cholinesterase and Rh group in them. Conclusion: a) we did not find any association between blood group ABO and Rh with any cholinesterase level in non-pregnant women, in men and in the general population. b) We could not assess the relationship between cholinesterase and Rh in pregnant women.

Keywords : cholinesterase; blood group ABO; blood group Rh; gestation; gender.

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