Abstract

SANCHEZ, William; SANTANA, Quindo; BUELVAS, José  and  CAMARGO, Rafael. Relationship between insulinemia and fatty liver in patients with normal body mass index and without a history of chronic alcohol consumption or diabetes mellitus. Acta Med Colomb [online]. 2011, vol.36, n.2, pp.73-77. ISSN 0120-2448.

There is a clear relationship between patients with nonalcoholic fatty liver disease (NAFLD) and hyperinsulinemia, especially in the presence of risk factors like diabetes mellitus (DM), dyslipidemia, and obesity. However, this can occur even without the risk factors mentioned above. Objective: to determine the relationship between NAFLD, and hyperinsulinemia in patients with normal body mass index (BMI) and without DM or chronic alcohol consumption. Materials and methods: cross, taking 59 adult patients, 29 women and 30 men in the Metropolitan University Hospital Foundation (FHUM) with no history of chronic alcohol consumption, with normal BMI and without DM with the following variables: age , sex, lipid profile, liver ultrasound and insulin. We used frequency distribution tables, multivariate analysis the relative risk (RR) and Chi square test with a confidence level of 95%. Results: in multivariate analysis the correlation between insulin level greater or equal to 8 IU, blood glucose was found that greater than 90 mg / L was 53.8% (7 cases) and insulin with glucose levels less than 8 greater than 90 mg / L was 43.5 (20 cases). 1.2246 with a relative risk (CI: 0.6460 to 2.3214), Chi square: p = 0.511 0.4315. Same with preset insulin levels with the following results with a relative risk: 1.1047 (CI 0.8655 to 1.4101) Chi square: p = 0.3151 1.0091. With an incidence of 8.47% with fatty liver diagnosed by ultrasonography. Regarding the average age was 24.5 years (± 10.4). Conclusions: the relationship of insulin resistance and NAFLD in this group of patients showed that the strength of the association RR away from a negative, which indicate no relationship between these two variables (Acta Med Colomb 2011; 36: 73-77).

Keywords : nonalcoholic fatty liver; hyperinsulinemia; dyslipidemia; diabetes mellitus; obesity.

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