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Acta Medica Colombiana

Print version ISSN 0120-2448


MUNOZ, Edison et al. Warfarin-Induced skin necrosis. Acta Med Colomb [online]. 2012, vol.37, n.3, pp.117-126. ISSN 0120-2448.

Warfarin-induced skin necrosis appears between 0.01% to 0.1% of patients. It affects mostly women with obesity and a history of thromboembolic disease after the fifth day of its administration, and is caused by a transient imbalance of procoagulant and anticoagulant systems, characterized by hemorrhagic blisters in areas with fatty tissue. (Acta Med Colomb 2012; 37: 138-141). We report the case of a warfarin-induced skin necrosis with fatal outcome.

Keywords : necrosis; skin; warfarin; anticoagulants; adverse effects.

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