Abstract

LOPEZ-PIEDRAHITA, Elizabeth et al. Hypereosinophilic syndrome and Churg-Strauss syndrome Spectrum of the same disease? New concepts. Acta Med Colomb [online]. 2014, vol.39, n.2, pp.174-184. ISSN 0120-2448.

Purpose of review: to review the current literature on the hypereosinophilic syndrome and establish which are the differences and similarities with Churg-Strauss syndrome. Source of data: structured review of the medical literature in databases Pubmed, Medline and Cochrane. Study selection: the search was limited to review articles, management guidelines and meta-analysis with no limits on language or publication date, using the MESH terms: hypereosinophilic syndrome, eosinophilic, Churg-Strauss syndrome. These were coupled to terms like:update, review, association. Data extraction: reading of the summary of 232 studies was made. Of these, 111 that were representative for the subject of this review, were selected, and after an ordered classification system, the wording was performed. Conclusions: The hypereosinophilic syndrome comprises a heterogeneous group of diseases with varied clinical presentations; for some authors, Churg-Strauss, more recently known as eosinophilic granulomatosis with polyangiitis, is part of this great syndrome, but for others these should be considered as separate entities. (Acta Med Colomb 2014; 39: 174-184).

Keywords : hypereosinophilic syndrome; eosinophilia; Churg-Strauss syndrome; eosinophilic granulomatosis with polyangiitis; update.

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