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Acta Medica Colombiana

Print version ISSN 0120-2448


AGUILAR, Carolina  and  GUTIERREZ, Johnayro. Adrenal deficiency by hemorrhagic infarction in antiphospholipid syndrome. Acta Med Colomb [online]. 2014, vol.39, n.4, pp.378-382. ISSN 0120-2448.

Two cases of primary adrenal insufficiency associated with unilateral or bilateral hemorrhage of the adrenal glands in the context of antiphospholipid syndrome (APS) are described: one patient with apparent picture of lung infection and subsequent diagnosis of adrenal failure, pulmonary infarction and primary APS and another patient with longstanding APS entering the emergency room with abdominal pain, asthenia, hypotension and hyponatremia. The abdominal images reported bilateral adrenal hemorrhagic commitment in one case and unilateral in the other. Both cases had low levels of serum cortisol and high adrenocorticotropic hormone and received hydrocortisone management with improvement of symptoms and normalization of blood pressure and electrolyte disorder. Antiphospholipid syndrome can be a cause of bleeding and thrombosis in any organ, leading to primary adrenal insufficiency as one of its complications.

Keywords : adrenal insufficiency; antiphospholipid syndrome.

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