Abstract

LANDAETA, María Eugenia et al. Atypical presentations of histoplasmosis. Acta Med Colomb [online]. 2015, vol.40, n.3, pp.254-259. ISSN 0120-2448.

Histoplasmosis is a granulomatous disease caused by Histoplasma capsulatum. It causes a wide spectrum of clinical manifestations, being the pulmonary the most common one. In some cases disseminated forms with involvement of one or multiple organs are manifested with atypical characteristics difficult to recognize. The pathogenesis of this disease is equal to that of TB and co-infection has been described. Three cases of infrequent presentation of histoplasmosis: elderly, co-infection with mycobacteria, atypical presentations and review of the literature are presented. The first case involved a 19-year-old with cerebral abscess. The second and third cases were for people over 60, co-infected with Histoplasma capsulatum and Mycobacterium sp, with joint involvement and gynecological disease, respectively. In Venezuela, endemic area for histoplasmosis, the doctor is required to have a high index of suspicion about this entity, taking into account factors such as age and epidemiology. (Acta Med Colomb 2015; 40: 254-259).

Keywords : histoplasmosis; tuberculosis; brain abscess; septic arthritis; Mycobacterium tuberculosis; itraconazole.

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