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Acta Medica Colombiana

Print version ISSN 0120-2448


FIGUEROA, Claudia Lucía et al. Glycosylated hemoglobin and cardiovascular events in diabetic patients of a university hospital. Acta Med Colomb [online]. 2018, vol.43, n.2, pp.74-80. ISSN 0120-2448.


the prevalence of cardiovascular comorbidities generated by Diabetes Mellitus is unknown globally in Colombia and is further unknown locally.


to determine the prevalence of cardiovascular events according to the levels of glycosylated hemoglobin (HbA1c), at the University Hospital of Santander.

Material and Method:

a cross-sectional, retrospective analytical observational study with patients from the internal medicine service of the University Hospital of Santander in 2013.


the prevalence of diabetes was 3l.2% (HbA1c>6.5%); of these 52.2% were women and the majority (70.45%) received pharmacological treatment. Although acute myocardial infarction (10.9%) was the most frequent event, the frequency of the different cardiovascular events as a reason for consultation was not related to any level of HbA1c. However, HbA1c> 9% in patients> 65 years had a risk of stroke, but without statistical significance. Among patients with HbA1c> 9%, 62.02% received <4 doses / day of medication (p = 0.000), with a high prevalence of in-hospital death (88%) with an OR of 2.08 (95% CI: 0.85-5.1; p = 0.107). It was found in the exploratory analysis with some relevant independent variables certain predictive behavior of HbA1c levels not so high <9% (AROC 0.67) and others, for in-hospital death (AROC 0.7).


in the population analyzed, the prevalence of cardiovascular events in the population with HbA1c >6.5% was 3l.06%; the category HbA1c> 9% was associated with greater in-hospital death; HbA1c <9% was associated with a higher dose of tablets for treatment. (Acta Med Colomb 2018; 43: 74-80).

Keywords : diabetes mellitus type 2; prevalence; glycosylated hemoglobin; myocardial infarction; cerebrovascular accident; peripheral arterial disease; heart failure; hospital mortality.

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