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Acta Medica Colombiana
versión impresa ISSN 0120-2448
Resumen
CONTRERAS, Kateir et al. Pachymeningitis and crescentic glomerulonephritis in p-ANCA vasculitis. Acta Med Colomb [online]. 2018, vol.43, n.2, pp.107-110. ISSN 0120-2448.
Vasculitis associated with antibodies against the neutrophil cytoplasm they form multisystemic pathologies characterized by affecting small vessels. Central nervous system involvement has been described in 2 - 8% of cases, rarely at the beginning of the clinical picture.
This corresponds to the case of a 67-year-old man with p-ANCA vasculitis, who debuted with proptosis, pachymeningitis and severe dysphagia. Subsequently, renal deterioration, the need for hemodialysis, cyclophosphamide and therapeutic plasma exchange, with which it reaches criteria of partial remission and dialysis discharge.
ANCA vasculitis is associated with a wide range of nonspecific signs and symptoms. The age of onset, initial creatinine and dialysis requirement are prognostic factors. The timely initiation of treatment is fundamental, requiring therefore a high index of suspicion. (Acta Med Colomb 2018; 43: 107-110).
Palabras clave : exophthalmos; vasculitis associated with antineutrophil cytoplasmic antibodies; dysphagia; glomerulonephritis; nervous system.