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Acta Medica Colombiana
Print version ISSN 0120-2448
Abstract
GARCIA-CASTELLANOS, Angie Tatiana; GUZMAN-LOPEZ, Julieth Alexandra; DIAZ-ACOSTA, Julio César and RAMIREZ-VELANDIA, Andrés Felipe. Primary orbital leiomyosarcoma. Acta Med Colomb [online]. 2021, vol.46, n.2, pp.42-45. Epub Nov 24, 2021. ISSN 0120-2448. https://doi.org/10.36104/amc.2021.1937.
Leiomyosarcoma is an aggressive mesenchymal malignant tumor which rarely presents in head and neck structures. There are few cases published in the literature, and clinical suspicion, diagnosis and early treatment are considered to be essential for dealing with the adverse outcomes derived from its poor prognosis. We report the first case of primary orbital leiomyosarcoma in Colombia, diagnosed in an older adult who consulted due to eight months of progressive growth of the left frontotemporal region along with dysarthria, vision loss and ipsilateral painful proptosis. Imaging studies revealed a large osteolytic lesion involving the orbit and central nervous system. An incisional biopsy was performed, reporting high-grade leiomyosarcoma. Once metastasis was ruled out, complete excision of the lesion was ordered, along with radiation therapy. After 10 months of close follow up, the patient had progressed well, with no local recurrences or distant metastases. (Acta Med Colomb 2021; 46. DOI: https://doi.org/10.36104/amc.2021.1937).
Keywords : leiomyosarcoma; orbit; immunohistochemistry; sarcoma.