Abstract

RESTREPO-VALENCIA, CÉSAR AUGUSTO; DOMINGUEZ-VINAYO, ÉDGAR H.  and  OROZCO-DE LA HOZ, CARLOS. Chloroquine-induced renal phospholipidosis. Acta Med Colomb [online]. 2022, vol.47, n.1, pp.49-54.  Epub May 06, 2022. ISSN 0120-2448.  https://doi.org/10.36104/amc.2022.2192.

This is the report of a patient being treated with chloroquine for an approximately 10-year history of rheumatoid arthritis, with a significant cumulative dose and documented progressive kidney function deterioration, non-nephrotic proteinuria and involvement of the proximal muscles of the extremities. The kidney biopsy showed zebra bodies in the podocytes. Fabry disease was ruled out. Medication-induced phospholipidosis was diagnosed, in this case due to chloroquine. This case report reminds us of the importance of being aware of the possible side effects of medications. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2192).

Keywords : phospholipidosis; kidney; proteinuria; arthritis; rheumatoid; chloroquine.

        · abstract in Spanish     · text in English | Spanish     · English ( pdf ) | Spanish ( pdf )