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Acta Medica Colombiana

Print version ISSN 0120-2448

Abstract

SPROCKEL-DIAZ, JOHN JAIME et al. Early warning scores to identify the risk of clinical worsening or death in patients hospitalized for COVID-19. Acta Med Colomb [online]. 2022, vol.47, n.3, pp.1-.  Epub Apr 02, 2023. ISSN 0120-2448.  https://doi.org/10.36104/amc.2022.2225.

Background:

identifying patients at risk for negative outcomes is key for performing a timely triage and adapting the care intensity for patients with COVID-19. Early warning scores are rules that alert to the risk of adverse outcomes during hospitalization. We sought to validate the modified NEWS, NEWS-2 and COVID-19 Severity Index (CSI).

Methods:

a prospective observational multicenter study of patients hospitalized for CO VID-19 at three quaternary care hospitals in Bogotá, Colombia, between April and November 2020. The operating characteristics and areas under the ROC curve were calculated.

Results:

711 patients were included, in whom the AUC for death was 0.68, 0.58 and 0.68, and for ICU admission was 0.61, 0.63 and 0.66 for mNEWS, NEWS-2 and CSI, respectively. The CSI had the greatest sensitivity for ICU admission or death (87.6 and 90.0%) and NEWS-2 had the greatest specificity (76.8 and 75.5%).

Conclusions:

the three early warning scores had a low to moderate performance in pre dicting ICU admission or death in patients hospitalized for COVID-19. (Acta Med Colomb 2022; 47. DOI:https://doi.org/10.36104/amc.2022.2225).

Keywords : COVID-19; prognosis; clinical prediction rules; death; intensive care; early warning scores.

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