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Acta Medica Colombiana

Print version ISSN 0120-2448

Abstract

LASSO-OSSA, LINA MARÍA; SUAREZ-ANGARITA, LUIS HERNÁN; BALLESTEROS-HERNANDEZ, ÓSCAR ANDRÉS  and  ACOSTA-FRANCO, MAURICIO EDUARDO ANDRÉS. The clinical course and frequency of risk factors associated with mortality in severe COVID-19 ARDS in ICU. Acta Med Colomb [online]. 2023, vol.48, n.2, e2.  Epub Apr 01, 2024. ISSN 0120-2448.  https://doi.org/10.36104/amc.2023.2629.

Importance:

In light of the high frequency of patients with severe ARDS in the observed population, this article was written to describe the frequency of the risk factors that impact on mortality and thus increase the quality of care for these patients.

Objective:

To describe the frequency of risk factors associated with mortality in patients with severe COVID-19 ARDS hospitalized in the ICU of Clínica Belén de Fusagasugá from July 2020 to January 2021.

Design:

An observational, descriptive, retrospective study including 115 patients admitted to the ICU at Clínica Belén de Fusagasugá with severe COVID-19 ARDS from July 2020 to January 2021.

Results:

Among the 115 patients who met the inclusion criteria there was a COVID-19 fatality rate of 49%. The use of IMV was related to mortality (p=0.000). The comorbidities related to mortality were hypertension (p=0.005), heart disease (p=0.024) and COPD (p=0.004). The median age of the population was 74 years. There was a high correlation between age and mortality; all the mortality risk scales were significant, except COVID-GRAM. Complications were more frequent in those who died, but only acute kidney injury (p=0.000), gastrointestinal bleeding (p=0.024) and fungemia (p=0.027) showed statistical significance.

Conclusions:

The fatality rate for severe COVID-19 ARDS was 15%; the risk factors most frequently associated with mortality were: age, need for IMV, HTN, diabetes and COPD. A correlation was found between the severity scales used (like NEWS2, APACHE II, SOFA, and MuLBSTA) and mortality. (Acta Med Colomb 2022; 48. DOI:https://doi.org/10.36104/amc.2023.2629).

Keywords : Coronavirus infections; intensive care; SARS; respiratory distress syndrome; mortality.

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