Abstract

ERICSSON D, Coy  and  CUCA, Luis E. NOVEL OXOAPORPHINE ALKALOID AND OTHER CHEMICAL CONSTITUENTS ISOLATED FROM Pleurothyrium cinereum (LAURACEAE). Rev.Colomb.Quim. [online]. 2008, vol.37, n.2, pp.127-134. ISSN 0120-2804.

A new oxyprenylated oxoaporphine alkaloid 1,2-methylendioxy-9,10-dimethoxy- 3-isopentenyloxy-7H-dibenzo[de,g]quinolin- 7-one (Pleurotirine) was isolated from the ethanolic extract of leaves of Pleurothyrium cinereum (Lauraceae), which was purified using chromatographic methods. Its structure was elucidated by means of spectroscopic techniques (1H-NMR, 13C-NMR, 2D-NMR and MS). Together with this alkaloid were isolated thalicminine , ent-kaurenoic acid , xanthyletin , alloxanthoxyletin , dihidroflavokawin B , 3-methoxy-3, 4-methylendioxy-4, 7-epoxynor- 8.5- neolignan-7.8-diene and friedelin 8 They are reported for the first time for this species and genus.

Keywords : Pleurothyrium cinereum; Lauraceae; alkaloids; coumarins; diterpene; norneolignan.

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