Abstract

CALIXTO, L. C.  and  MARTINEZ, J. R.. Determination of Helicobacter spp. in glandular gastric mucosa of mules through the test of urease activity and histopathology. Rev. Med. Vet. Zoot. [online]. 2022, vol.69, n.2, pp.121-128.  Epub Aug 08, 2022. ISSN 0120-2952.  https://doi.org/10.15446/rfmvz.v69n2.103260.

Information on the presentation and predisposing factors of Mule Gastric Ulcer Syndrome (MGUS) is scarce, compared to Equine Gastric Ulcer Syndrome (EGUS) and donkeys. Within the multifactorial nature of this syndrome, helicobacteriosis has been studied in other species. The objective of this work was to establish the presence of Helicobacter spp. in gastric mucosa of mules, through the rapid urease test (RUT) and histopathological analysis. Less than 27% of the samples reacted to RUTs, with prolonged reaction times, and Urea Agar (gold test), with a lower percentage of positivity. Histopathology revealed chronic inflammatory processes, without the presence of curved-spiral bacteria. The RUTs were not conclusive in the determination of Helicobacter spp., a similar behavior reported in horses. More specific diagnostic tests and complementary procedures are required to explore the regions of the stomach in consideration of the number of representative samples.

Keywords : Helicobacter spp.; mule; ulcer; ureasa; histopathology.

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