Abstract

MARTINEZ PACHECO, Fabio H  and  ZAMBRANO BENITEZ, Claudia Patricia. Case report and literature review: Hyperpyrexia as side effect following the administration of sub-lingual misoprostol in the management of post-partum hemorrhage. Rev. colomb. anestesiol. [online]. 2013, vol.41, n.1, pp.65-68. ISSN 0120-3347.  https://doi.org/10.1016/j.rca.2012.08.004.

This is a patient with post-partum hemorrhage (PPH), secondary to uterine atony managed with sub-lingual misoprostol 1000μg . Hyperpyrexia resulting from the route of administration of the drug and the clinical presentation of the condition, give rise to diagnostic difficulties and special interventions during the management process. A literature review on misoprostol, its pharmacological profile and side effects concluded that sub-lingual misoprostol results in a maximum concentration and is associated with the highest incidence of side effects as compared to other routes of administration.

Keywords : Fever; Misoprostol; Hyperpyrexia; Postpartum haemorrhage.

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