Abstract

MALAVERA ANGARITA, Mayra Alejandra et al. Pathophysiology and treatment of phantom limb pain. Rev. colomb. anestesiol. [online]. 2014, vol.42, n.1, pp.40-46. ISSN 0120-3347.  https://doi.org/10.1016/j.rca.2013.09.012.

Introduction:Phantom limb pain may be present in up to 80% of patients subjected to amputation because of trauma or peripheral vascular disease. Several factors have been associated with its occurrence, including pre-amputation pain, the etiology, and the amputation level. Objective: To review the current status of the pathophysiological mechanisms, treatment Opioid options and their efficacy for the management of phantom limb pain. Method:Non-systematic review of the literature in PubMed and Cochrane, of articles describing the pathophysiology and treatment of phantom limb pain. Results and conclusions: The proposed pathophysiological mechanisms are still in research and include peripheral, central and psychological factors. Treatment options are still limited, and less than 10% of patients report long-term improvement.

Keywords : Phantom Limb; Pain; Analgesics; Opioid; Electric stimulation; Autonomic nervous system.

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