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Revista Facultad Nacional de Salud Pública

Print version ISSN 0120-386XOn-line version ISSN 2256-3334


CARDONA-ARIAS, Jaiberth Antonio; SALAS-ZAPATA, Walter Alfredo  and  CARMONA-FONSECA, Jaime. Research profile in pregnancy-associated malaria: systematic review 1925-2018. Rev. Fac. Nac. Salud Pública [online]. 2020, vol.38, n.3, e338621.  Epub Dec 01, 2020. ISSN 0120-386X.


To describe the profile of publications on pregnancy-associated malaria worldwide, based on countries, types and years of study, 1925-2018.


Systematic review of the literature, by monitoring the PRISMA guide and guaranteeing the reproducibility of the variable selection and extraction protocol. Twelve search strategies were applied in PubMed, Science Direct, SciELO and Google Scholar. Qualitative synthesis was performed using frequencies for the country, year of study and type of research.


3362 publications were screened, of which 617 complied with the protocol. 81.5% were from Africa, 9.9% from Asia and 5.3% from America. The highest proportion of publications was after 2009. 65.8% were observational studies; 22.0%, clinical trials, while qualitative studies, economic evaluation studies or evaluation studies of programs and policies accounted for less than 5%. No studies of diagnostic tests, evaluation of programs or qualitative research were found in America.


The profile of publications shows the predominance of traditional-positivist epidemiological research and its concentration in Africa, which implies challenges for health and research agendas in public health, but with greater need in America.

Keywords : Malaria; pregnant women; pregnancy-associated malaria; epidemiological studies, public health; social sciences.

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