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Print version ISSN 0120-4157
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SILVA, Federico A; RUEDA-CLAUSEN, Christian F  and  RAMIREZ, Fabián. Extrapontine osmotic myelinolysis. Biomédica [online]. 2005, vol.25, n.2, pp.167-169. ISSN 0120-4157.

Extrapontine osmotic myelinolysis is a rare nervous system complication. Symptoms of this malady were presented during the clinical examination of a 49-year-old alcoholic male, who arrived at the hospital emergency room in a state of cardiorespiratory arrest. After resuscitation methods were applied, the patient was found in metabolic acidosis (pH 7.014) and was treated with sodium bicarbonate. Forty-eight hours later, sodium levels in the patient had risen from 142 to 174 mEq/l. During the period of clinical observation, the patient showed signs of cognitive impairment, disartria, bilateral amaurosis, hyporeflexia and right-half body hemiparesias. After 72 hours, computer tomography was applied; this showed a bilateral lenticular hypodensity with internal and external capsule compromise. One month later, when the patient was referred to another institution for rehabilitation, the patient showed cognitive impairment, bilateral optic atrophy, residual disartria, bradikynesia and double hemiparesia.

Keywords : osmotic myelinosysis; extrapontine osmotic mielinolisis; hyponatremia; alcoholism.

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